Bruker Corporation

Returning Candidate?

Master or PhD in Chemistry or Physics working in Clinical High-Resolution NMR Spectroscopy (m/f)

Master or PhD in Chemistry or Physics working in Clinical High-Resolution NMR Spectroscopy (m/f)

Anzahl offener Funktionen  
Regular Full-Time
Datum der Veröffentlichung 

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As one of the world’s leading analytical instrumentation companies, Bruker covers a broad spectrum of advanced solutions in all fields of research and development.
All our systems and instruments are designed to improve safety of products, accelerate time-to-market and support industries in successfully enhancing quality of life.
We’ve been driving innovation in analytical instrumentation for 50 years now. Today, worldwide more than 6,000 employees are working on this permanent challenge, at over 70 locations on all continents.



Master or PhD in Chemistry or Physics working in Clinical High-Resolution NMR Spectroscopy (m/f)



Division:                                                         AIC

is directly reporting to:                                   Group Leader Clinical Applied NMR Development

gets project based reports from:                   Technical Product Manager

Location:                                                        Rheinstetten / Karlsruhe / Germany



Specific Objectives:

Developing and implementing automated methods for clinical/translational high-resolution NMR including related support of cooperation partners and customers.




  • Support the development and validation of automation methods for clinical/translational High-Resolution NMR analysis including sample preparation, acquisition, basic data analysis (statistical and quantification) and reporting.
  • Support further development and validation of Bruker’s bodyfluid NMR SOPs, the B.I Methods, and data analysis tools for NMR based Lipoprotein subclass analysis, ie. B.I.LISA™, and NMR based quantification of metabolites in urines, ie. B.I.Quant-UR™ methods and related QC methods.
  • Support development of HR-MAS methods for NMR in biological tissues including related support of customers and cooperation partners working in that field.
  • Develop routines for automated instrument and quality control tailored to the needs of clinical/translational High-Resolution NMR.
  • Develop programs for automated installation and setup of NMR bodyfluid SOPs.
  • Support integration of new developments into ISO 17025, ISO 15189 and ISO 13485 accreditation as well as potential IVD-CE certification.
  • Support method development team for clinical/translational analysis in all related projects including running large scale NMR screening studies with up to several thousand samples.
  • Support SLS-service-team regarding validation, installation, maintenance and customer support for IVDr™ and potential future platforms
  • Support lean innovation concepts
  • Representation of the company and promotion of the product portfolio at congresses or seminars



Main Interaction

  • CTO
  • Clinical Applied NMR Development Team
  • Sales Team Clinical NMR
  • Clinical Market Management and MARCOM
  • Technical Product Manager
  • SLS Team
  • Cooperation partners of Clinical Applied NMR Development Team



  • Master or PhD in chemistry or physics.
  • Proficiency in NMR theory and experiment with several years (>5 years) of working experience.
  • Sound knowledge of NMR instrumentation, hardware and software as well as of pulse programming and AU (C/C++ and Python based) programming.
  • Experience in NMR based analysis of biological mixtures, i.e. quantification of metabolites and application of chemometrics and multivariate statistics would be a strong advantage.
  • Working experience with HR-MAS NMR would be an advantage.
  • Working experience in clinical epidemiology would be an advantage.
  • Ability to successfully collaborate with German and international collogues, collaboration partners and customers is a must.
  • Being a team worker with excellent communication skills is a must.
  • Willingness to strongly contribute to challenging developmental as well as to daily routine work in clinical High-Resolution NMR.
  • Willingness to travel worldwide (up to 30%).
  • Proficiency in English is mandatory, German is an advantage, additional languages welcome.